The analogues were obtained from key compound diethyl 8-deaza-5,6,7,8-tetrahydroaminopterin 8 following the catalytic reduction of the pyridine ring of diethyl 8-deaza aminopterin 5.
It could be precipitated with addition of diethyl ether as described by Bell et al. (2003).
Finally, 3 mL of diethyl amine were added to the mixture.
The residual syrup (264 mg) crystallized on addition of diethyl ether to give 6.
For each 1 mL of TFA solution, 10 mL of diethyl ether was used.
Thirty-two derivatives of barbituric acid as zwitterionic adducts of diethyl ammonium salts were synthesized.
The synthesis of N,N-diethyl-3,5-difluorobenzene sulfonamide was achieved via the one-step reaction of diethyl amine with commercially available 3,5-difluorobenzenesulfonyl chloride.
The more women douched, the higher their exposure to a form of diethyl phthalate (DEP), the study found.
For example, the addition of diethyl malonate into benzaldehyde would produce only one product.
