Among the adult devices used with children are stents, defibrillators, pacemakers, artificial mitral valves, chemotherapy delivery devices, kidney dialysis systems, and metal implants that help straighten a spine or replace a piece of bone.
The reconstruction of large defects after head and neck cancer resection often requires composite tissue transfer to replace a combination of bone, muscle and mucosa.
Bone grafting is a surgical procedure that replaces a missing bone with material from the patient's own body, using an artificial, synthetic, or natural substitute.
Dogs underwent surgery to replace a section of tibial bone with a bioresorbable scaffold.
The first person to recover from HIV, Timothy Ray Brown, had his immune system wiped out during leukaemia treatment and then replaced with a bone marrow transplant from someone with the mutation.
The unique nature of science and technology created at BioMediTech can be illustrated by the fact that in 2008, for the first time in the world, a patient's upper jaw was replaced with a bone transplant cultivated from the stem cells isolated from the patient's own fatty tissue (Sotarauta and Mustikkamäki 2015).
A 2 × 2 cm bone block was removed and replaced with a bone graft from the iliac crest, and a Matta plate (Stryker®, Michigan, United States) was applied.
There were a number of attempts in the past to replace bone loss with bone replacement materials.
Partial physeal arrest is particularly apt to produce progressive angular deformation when a bridge of sclerotic bone forms eccentrically between the epiphyseal ossification centre and the metaphyseal bone, replacing a segment of the physis and the zone of Ranvier.
However, despite the successful development of bone mimetic materials that can replace damaged bone from a structural point of view, most of the available bone biomaterials often do not induce sufficient formation of blood vessels and nerves.
