Sentence examples for repertoire variability from inspiring English sources

Notably, analysis of CD8+ SP cells for which the TCR repertoire variability had been reduced by expression of the MHC Class I-restricted H-Y or P14 TCR transgene (tg) [26], [27] inferred an altered TCRαβ selection in the mutant mice (data not shown).

For our inter-species comparison of OR repertoire variability, we use the entire human and mouse OR intact gene repertoires, the only two species for which we have well characterized repertoires from finished genomic sequence (the dog OR repertoire is not yet fully described [8] and the draft of the chimpanzee genome has relatively low coverage for this type of analysis [10]).

Interpretative repertoires acknowledge that variability, inconsistencies and contradictions occur within everyday discourses.

CONCLUSION: Patients with DiGeorge syndrome, skin rash, and lymphadenopathy should undergo analysis of naive T-cell numbers and of T-cell receptor beta variability segment repertoire to determine whether they are athymic, even if they have T cells with mitogen responsiveness.

However, challenging clonal variability, limited vector repertoire and insufficient genome annotation have hampered further developments.

A similar scenario, described also by others [36], highlights that the degree of inter-individual variability in Th repertoire composition provides a challenge when assessing functional consequences of gene variants.

Hepatitis C virus, with its extreme variability of sequence repertoire, is a difficult target for vaccine design.

Further studies are needed to characterise the influence of this variability on the repertoire of deiminated target proteins.

The objective was to provide a systematic description of total rhs diversity and so gain an insight into variability in rhs repertoire between genera.

Large variability increases the repertoire of individual differences, which may be positively selected in order to cope with demands for efficient ribosome usage without affecting the function of the final protein product that is mainly determined by secondary and tertiary structures of protein polypeptide.

When looking at the size of T3E repertoires, we observed a large variability.