Sentence examples for repertoire selection from inspiring English sources

As such, it is proposed that tapasin is a major determinant of peptide repertoire selection for class I-restricted presentation in normal antigen presenting cells.

Using single-cell PCR and high-throughput sequencing, we have exploited this system to scrutinize T cell repertoire selection and evolution.

Music students need library search skills to find music resources of scores and sound recordings for study, repertoire selection and performance practice.

Here we review recent advances in the field, focussing on structural data pertaining to biased TCR usage, and discuss the implications for T-cell repertoire selection, MHC restriction and therapeutic development.

However, since these polyreactive antibodies derived their secondary antigens from repertoire selection, the identity of the secondary antigen cannot be pre-determined.

Further, structurally plastic regions have been shown to preferentially attract new binding ligands in vitro by repertoire selection of non-biased libraries of peptides and proteins [49], [51].

Studying the involvement of cytokines in the development of Treg and other T cell-subsets will shed light on modulation, by peripheral immune-responses, of T cell differentiation and TCR-repertoire selection in the thymus.

A recent study [10], using challenges of vaccinated and naïve mice, has highlighted another, potentially significant element of the immune escape repertoire: the selection of 'adsorptive mutants', showing enhanced binding to target cells.

The versatile nourseothricin, streptomycin/spectinomycin and spectinomycin resistance loxP cassette vectors described here extend the repertoire of antibiotic selection markers for genetic manipulation of diverse bacteria that are susceptible to aminoglycosides and aminocyclitols.

53 Studies in wild type and MOG-deficient mice showed that potentially pathogenic anti-MOG T cells are not completely cleared from the immune repertoire during thymic selection.

The existence of an antitumour immune repertoire in a selection of patients forms the rationale for the development of cancer immunotherapy.