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Ryu, H. et al. Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway.
The structures reveal an extended horseshoe leucine-rich repeat (LRR) receptor architecture that binds, with its concave side, the ligand furin-like repeats via an intimate interface.
Hyaluronic acid (HA) is a polyanionic natural polymer occurring as linear polysaccharide composed of glucuronic acid and N-acetylglucosamine repeats via a β-1,4 linkage.
Instead, the RNA-binding domains of TERT interact with TR to facilitate the elongation of the telomere repeats via the catalytic activity of the RT domain [11], [12], [13], [14], [15].
However, Pol IV and Pol V subunits localize within the nucleus [5], [8], [12] and are required for the silencing of transgenes, retrotransposons and other endogenous repeats via a 24 nt siRNA-dependent DNA methylation pathway [13].
In addition, for NCU07846 the zinc-finger is the only annotated DNA-binding domain in this protein (Fig. 2a), suggesting that it recognizes TTAGGG repeats via this domain.
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The follow-up screening consisted of cytological and repeat VIA screening.
Ms. Chen closed her recital at the grand piano, with Alvin Lucier's "Nothing Is Real," a deconstruction of the Beatles' "Strawberry Fields Forever," first played live, then repeated via a recording of the live performance, heard from a small speaker inside a teapot.
All of these comments and actions were repeated, via the media, to hundreds of millions.
One and two weeks later assessments were repeated via the internet while patients were at home.
The follow-up time ranges from 4 to 6 weeks and 1 year, at which the assessments will be repeated via face-to-face interview, or via telephone interview if necessary.
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