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Andrade, M. A., Perez-Iratxeta, C. & Ponting, C. P. Protein repeats: structures, functions, and evolution.
Complex repeats structures have very important biomedical functions.
Therefore, their real repeats structures can be easily detected by RepeatScout [ 26].
The repeats structures including lengths and copies were detailed in the Appendix and the link detected repeats and their copies in Table 6 in supporting data.
The repeats structures including lengths and copies are detailed in the Supplementary Materials Appendix and are freely available at http://222.200.182.71/swa/Table6.rar.
Their repeats structures can be easily analyzed by RepeatScout [ 26], which is a very effective and sensitive de novo repeats identification method for large genomes and is freely available at http://bix.ucsd.edu/repeatscout/.edu/repeatscout/
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Other elegant model systems of repeat structures suggest structural dynamics but share the same limitations.
Immunoglobulin fold and tandem repeat structures in proteoglycan N-terminal domains and link protein.
Haeusler, A. R. et al. C9orf72 nucleotide repeat structures initiate molecular cascades of disease.
Instead of resolving complex repeat structures on the whole-genome level, we reconstructed the sequences of 100 150 kb BACs.
See how the MIT researchers' algorithm automatically detects and visualizes variations between repeating structures in a single image.
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