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Training of project nurses will ensure consistency of approach and will be confirmed by repeating outcome data collection for 5% of the sample.
The linear mixed effects models will account for the within-subject correlations that are produced when repeating outcome measurements in individual subjects over time.
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According to this traditional view, a scientific hypothesis may be tested and verified by obtaining the repeated outcome of substantiating observations.
The methods are based on a simple model for comparing two phases, where the level of the outcome is stable within each phase and the repeated outcome measurements are independent.
Primary analyses used the GENMOD procedure in SAS to develop generalized estimating equation (GEE) models [35] using an exchangeable correlation structure which examined the relationship between the repeated outcome measure of failure to remit at each assessment point and the independent variables.
GENMOD procedures were used to analyze repeated outcome measurements of glycemic control.
Model 3 described the relationship among the repeated outcome measures (alternating logistic regression) [ 55].
The original audit found that only 30% (18/61) of case-notes contained at least one repeated outcome measure.
Due to this repeated outcome of all fermentation runs, the subsequent analyses were mainly performed with culture supernatants.
Different covariance patterns for the repeated outcome measures will be explored and the most appropriate structure will be used.
These ECG measures were treated as repeated outcome measures, and each individual contributed 48 outcome data points on each of the three ventricular repolarization variables.
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