While the genome assembly is too fragmented to assay for clusters of piRNA producing repeats, we confirmed that piRNAs in the testis are derived from both conserved repeats and tammar-specific repeated elements (specifically LTRs).
For this reason, the above analysis was repeated focusing specifically on LGC and HGC genes.
To determine whether HC2 results varied by LMP, we assessed the frequency of positive HC2 results varied by LMP, and then repeated analyses specifically for 'borderline HC2 results,' previously defined as 0.8 1.5 pg ml−1 (Federschneider et al, 2004).
Here, we demonstrate that TALE repeats specifically recognize a DNA-RNA hybrid where the DNA strand determines the binding specificity.
The RNA repeats specifically sequester or change the expression levels of several RNA-binding proteins, leading to aberrant splicing of many target genes.
Oriented peptide library analysis indicated that the BARD1 BRCT repeat specifically recognizes pS-[D/E]-[D/E]-E.
The observed excess of IRs does not result from the presence of long dinucleotide repeats, specifically (ApT) n or (TpA) n.
Other mutations such as some splice variants and glycine substitutions in the GXY collagen repeats, specifically in exons 1-20, confer later onset disease [ 2].
The tetra-nucleotide repeats, specifically, poly (AAAG n, poly (AAAT n, poly (AAAC n, and poly (AATG n, were more commonly observed compared with other motifs, and collectively they added up to 72% of the tetra-nucleotide repeats.
Other transgenic DM1 mouse models are inducible models that express 960 CTG repeats specifically in the heart (59) or skeletal muscle (60) or 200 CTG in both of these tissues (45).
