Sentence examples for repeat strongly from inspiring English sources

This individual is a late-onset, mildly affected FRDA patient, who carries relatively short GAA repeat expansions and has higher baseline frataxin levels than the other patients, suggesting that HDAC inhibition may be more effective when long GAA repeat strongly downregulate FXN expression.

The GC content of approximately 48% compared with an average GC content of approximately 53% for the whole genome of C. ulcerans together with the 100 bp directed repeat strongly indicate horizontal gene transfer [ 66].

Our results reveal a complex genomic architecture in the i(17q) breakpoint cluster region, characterized by large (∼38 49-kb ∼38 49-kbomic, low-copalindromic strongly suggesting that somatic rearrangements are not random events but rather reflect susceptibilities due to the genomic strepeats.

The similarities between the trees obtained using Cas9, Cas1, Cas2, Csn2/Csn2-like, and the CRISPR-repeat strongly suggest that the CRISPR-Cas system is inherited as a complete module (Godde and Bickerton 2006; Kunin et al. 2007; Horvath et al. 2009).

In yeast, these trinucleotide repeats strongly stimulated mitotic crossovers and were preferred sites for chromosome breakage [ 40], double-stranded DNA breaks and terminal deletions.

Interestingly, the presence of stretches of conserved repeat variants strongly suggests that the new repeat sequence comes from the duplication of the adjacent repeat sequence (e.g. Table S6).

Conversely, targeted expression of human MBNL1 to Drosophila eye precursors expressing 480 interrupted CUG repeat transcripts strongly suppressed the rough eye phenotype, whereas expression of the unrelated GFP protein under the same conditions showed no effect (Figure 3F, G). 60 CUG repeat RNA caused a milder effect on external eye morphology, only altering mechanosensory bristles (Figure 3D, E).

Interestingly, line 1 had multiple alleles with smaller repeat length, strongly indicating repeat instability during reprogramming.

Therefore, we repeat and strongly advocate the recommendation to study tailoring as compared to other intervention methods, such as generic health education.

If CCTTT repeat length strongly influences NOS2 transcription, then we would expect there to be a significant correlation between CCTTT repeat length and serum NO levels or NO/ET-1 ratios.

Then we asked whether the observed nucleotide sequence differs from the random sequences in the frequency of short nucleotide repeats, and thus in terms of stability We again first focused on mononucleotide repeats, and found that these repeats are strongly under-represented in coding regions of M. tuberculosis.