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A repeat range finding test was conducted at 0.002, 0.02, 0.2 and 2 mg/L with an untreated control.
In the repeat range finding test, all fish in the highest dose group (2 mg/L) experienced difficulties in respiration within 1 h.
Fish obtained from Selcoth Fish Farm in Moffat, Scotland were used for the initial and repeat range finding tests, while fish from Brow Well Fisheries Ltd., Skipton, England were used in the definitive test.
Fish were kept in 12-L (initial and repeat range finding tests) and 17-L (definitive test) tanks of reconstituted freshwater (RFW) according to the formula recommended by OECD Guideline 203 [9].
For the repeat range finding test and the definitive test, a reduced pH was not required and the holding and test medium were maintained at a pH range of 6.0 8.5.
The normal repeat range is from 25 up to 42 45 units [6].
Similar(48)
The [GGGCC] repeat ranged from 2 to 5 tandem copies, the [CT] repeat ranged from 9 to 16 tandem copies, and the [TAAA] repeat ranged from 8 to 13 tandem copies (Table 1).
The distribution of the number of motif repeat ranged from 4 - 30 repeats (Table 1).
The polymorphism in the IGF1 gene is a tandem dinucleotide repeat, ranging in size from 12 to 23 repeats.
In normal individuals, the repeat ranges from 10 to 29 and increases up to 4500 in SCA10 patients.
Alternating intervals of climatic amelioration led to repeated range expansion, most recently from the close of the last glacial period about 10,000 years ago.
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