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Although SAT5 was originally thought to be a non-protein coding repeat, improvements in the annotation of the Arabidopsis genome sequence during the course of our study revealed that genes encoding small cysteine-rich peptides (CRPs) and related CRP pseudogenes are embedded in the SAT5 repeat monomer (Additional file 2: Figure S2).
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In this context, it is becoming increasingly accepted that successful long-term preservation of digital data depends upon repeated incremental improvements or curations taking place in 5 10 year cycles.
Where audits have been repeated, progressive improvements in standards can be shown, for example the 2011 re-audit of bedside administration (the third audit) showed an improvement in the numbers of patients wearing wristband at the time of transfusion and better monitoring (National Comparative Audit, 2011).
However, when the abdominal CT was repeated, no improvement in the mass appeared and it was even slightly enlarged.
With ongoing antibiotics a repeat echocardiogram showed improvements in the vegetations.
Some of the repeat cycles showed improvements following actions guided by the initial cycle, as in the Mexico medical school audit, in anti-corruption efforts in Nicaragua, and in reproductive health services in the Maldives.
Given that high state anxiety in those women receiving an inadequate smear test result predicted nonattendance for a repeat smear test, improvements in communicating these ideas should not only reduce the distress experienced by women receiving this result, but should also achieve higher reattendance and hence better clinical outcomes from the screening programme.
The White House has been clearly cognizant of the damage done to its credibility by its repeated promises of improvements being undone by rising sectarian violence in Iraq.
More significant issues such as why the government-provided security was so inadequate, despite Bhutto's repeated pleas for improvements—have been subsumed, at least temporarily, by a climate of suspicion and political maneuver in advance of the elections.
Problems experienced last year as campers faced lengthy queues to get into car parks because of heavy rains were not repeated this year with improvements to the entrances and traffic systems helping ease arrivals.
More significant issues — such as why the government-provided security was so inadequate, despite Bhutto's repeated pleas for improvements — have been subsumed, at least temporarily, by a climate of suspicion and political maneuver in advance of the elections.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com