Sentence examples for repairing pathway from inspiring English sources

ZFN technology has been widely used to introduce DSBs at endogenous loci in animal systems to generate allele mutations (a small deletion or insertion of bases at the break sites) and to achieve allele replacement to fix a defective allele, for example, through the NHEJ and homologous recombination repairing pathway, respectively.

As the result, the broken DNA is repaired through homologous recombination (HR) or NHEJ repairing pathways.

Proteins of the nucleotide excision repair pathway repair DNA damage.

A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.

However, apurinic sites may be repaired rapidly via the base excision repair pathway.

Collectively, we observed no cytotoxic effect of MS2-CtIP; rather, it activated the DSB repair pathway.

DSB repair pathway choice is influenced by a number of factors including cell cycle phase.

Symington, L. S. & Gautier, J. Double-strand break end resection and repair pathway choice.

Pai, et al. A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice.

These findings support an H3K36 chromatin switch in regulating DSB repair pathway choice.

The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder.