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Repair interactions are often observed between members of different institutional groups and nationalities, whereas reformulation interactions were mainly initiated by the Chair with intra-group members.
In this study, to assess the cooperative involvement of MutS, MutL, and MutS2 in DNA repair, interactions of MutS2 with MutS and MutL were examined by co-immuno precipitation assay.
SPR is a chip-based and label-free procedure that allows real-time monitoring of various replication and repair interactions involving DNA lesions.
SAXS data show that the solution structure is most consistent with an ensemble of ankyrin-BRCT models suggesting that the two domains sample a wide range of orientations with respect to one another, reminiscent of those seen for mismatch repair interactions.
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In fact, in our datasets the WRN protein has 14 DNA repair interaction partners, all of them belonging to the ageing-related class.
More precisely, XRCC5 was selected 2 times as the root node of a decision tree built by J48; and, out of XRCC5's 11 DNA repair interaction partners, 10 are ageing-related DNA repair proteins.
In addition to their classical transport function, NPCs have now been extensively implicated in transcriptional gene regulation and in DNA damage repair via interactions with the underlying chromatin.
They'll fund research on, for example, the development of new vectors or gene constructs for plants--such as those that introduce bacterial pesticides in plants--or the mechanisms of gene regulation, DNA repair, genetic interactions, molecular evolution, and genomics.
Several pieces of evidence also support a role for menin in DNA repair including interactions with FANCD2 and RPA [21], [24].
The protein structure and biochemical properties suggest it has a role in DNA repair, whilst interactions with other proteins indicate involvement in the regulation of gene expression [ 14].
Additionally, 9-1-1 may play a direct role in facilitating DNA damage repair via interaction with a number of DNA repair enzymes.
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