Exact(2)
While printed implants have previously been used to help correct congenital conditions, this operation used custom-printed models, guides, plates and implants to repair impact injuries months after they were sustained.
Our results demonstrate that specific defects in DNA repair impact the dopaminergic system and are associated with human PD pathology and might therefore constitute an age-related risk factor for PD.
Similar(58)
A wide variety of additional experimental evidence suggests that tissue repair impacts decisively on the final toxic outcome and any modulation in this response has profound impact in the final outcome of toxicity.
Gene set enrichment analyses (GSEA) revealed gene sets involving DNA repair impacted by modulating SPOP function.
These results are, however, based on in vitro analysis, and no studies have characterised the role of mutant p53 or whether aberrant mismatch repair impacts on the relationship.
However, when cell cycle checkpoint defects are combined with defective DSB repair, the impact is more than additive, consistent with the notion that cell cycle checkpoint arrest enhances the opportunity for DSB repair.
These modifications affect PCNA's activity in the bypass of lesions during DNA replication, the regulation of alternative damage processing pathways such as homologous recombination and DNA interstrand cross-link repair, or impact on the stability of PCNA itself.
This review will discuss the major contributions and recent progress in the C. elegans field to elucidate the complex networks involved in DSB repair, the impact of which extends well beyond the nematode phylum.
To evaluate how varicocele repair (VR) impacts pregnancy (PRs) and live birth rates in infertile couples undergoing assisted reproduction wherein the male partner has oligospermia or azoospermia and a history of varicocele.
Impaired DNA repair also impacts upon response to DNA damaging radiotherapy and chemotherapeutics [ 1].
A major question is the exact ship velocity to be allowed for, the determination of which is primarily an exercise in probability, balancing the economics of designing to a specified velocity against the cost of repairs after impacts at greater velocities.
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