Sentence examples for repair function of from inspiring English sources

Therefore, the "repair" function of OECs may require close contact with damaged neurons.

To further validate the DSB repair function of PARP2 and APLF, we treated APLF and PARP2-deficient cells with IR and used neutral comet assays to examine the DSB repair.

He purified the genes and reconstituted them in vitro ("in glass," or outside a living organism), leading to his discovery of the excision repair function of an enzyme known as uvrABC nuclease (excision nuclease, or excinuclease) in E. coli.

This repair function of PNKP is facilitated by its binding to the scaffold protein XRCC1, and phosphorylation of XRCC1 by CK2 at several consensus sites enables PNKP binding and recruitment to DNA damage.

The N-terminal domain is sufficient for the DNA repair function of dRecQ4.

KDO8PS derived from the MD simulation was optimized using the repair function of FoldX.

Our data suggest that the N-terminal region has no direct role in the DNA repair functions of APN-1 other than to target the protein to the nucleus and possibly to maintain its stability.

In general, bioinformatic and experimental studies suggest that genome configuration and copy-number or the protection and repair functions of sensitive bacteria do not have unique properties that predispose them to DNA damage or inefficient DNA repair [5], [20], [21].

Although the relevance of ITGA5 and ITGB6 to airway basal cell biology is largely unknown, several independent lines of evidence indicate their potential relevance to the stem/progenitor cell and tissue repair functions of airway basal cells.

Furthermore the detection of DSBs in pachytene spermatocytes and the abnormal chromatin structure in mature sperm confirm that the repair functions of ERCC1 are essential for normal germ cell maturation and suggest that none of the other NER proteins can compensate for its ablation.

Inhibiting the DNA repair functions of SETMAR in this way could be used to augment current chemotherapies.