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We report here the function of NRG1 in nerve repair and functional recovery in the PNS.
This study evaluated the relationship between timing of lingual nerve repair and functional sensory recovery.
Cast immobilization, surgical repair, and functional treatments are considered the treatment options in the scientific literature [11, 12].
This can be explained by the phenomena of non-functional retarded acellular repair and functional rapid cellular repair as discussed by Vardimon et al. [17].
The purpose of cell-based therapies is to apply living cells to guide and promote enhanced tissue repair and functional regeneration of an injured or diseased tissue.
Finally, optimised hMSC embedded microgels were shown to induce vascular repair and functional improvement in vivo in a mouse model of hind-limb ischemia.
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To examine if greater BMC cardiac retention translated into improved cardiac repair, morphometric and functional analyses were performed in 5 groups of rats administered with BMCs IV or IM and for the former in the presence or absence of fibrin 4 weeks after myocardial infarction (Table 1).
Although several clinical studies have documented hyaline-like repair tissue and functional improvements with ACI, its long-term efficacy remains controversial [ 1, 3].
Subsequent research suggested that such a clock model is violated for distantly related species; however, local clocks for individual genes can be applied due to similarities within groups in their metabolic rate, generation time, DNA repair efficiency, and functional constraints on particular genes [ 4, 14, 15].
To facilitate nervous system repair and improve functional outcomes, clinicians and researchers are utilizing therapies that provide proregenerative cues and structural support using exogenous extracellular matrix (ECM) derived neurological implants.
The administration of recombinant NGF protein into injured nerves has been shown to promote nerve repair and enhance functional restoration following nerve damages [9].
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