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Thus, we took advantage of using clonogenic assays to demonstrate, in vitro, self renewal features and multipotency of these recombined cells [4].
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Instead, in 1998, not long after he had ended his 26-year tenure at the Gewandhaus Orchestra to devote himself wholeheartedly to the Philharmonic, the board unceremoniously nudged him toward the exit, revoking the evergreen renewal feature of his contract extensions.
In a vintage renewal featuring some potentially improving young steeplechasers, the Paul Nicholls-trained Silviniaco Conti also looked a leading player before falling at the third fence from home.
There are novel opportunities for developing therapeutics by targeting the differentiation and self-renewal features of glioma.
It has been previously reported that many differentiation genes are transcriptionally repressed by Polycomb repressive complex 2 (PRC2) through bivalent chromatin modifications (carrying both H3K27me3 and H3K4me3 histone marks) to maintain the self-renewal features of embryonic stem (ES) cells.
The Notch signalling pathway is a key regulator of epithelial to mesenchymal transition (EMT) affecting migration and invasion of breast cancer cells [ 12], and several studies link EMT to the generation of cancer stem cells (CSCs) with mesenchymal and self-renewal features necessary for dissemination and formation of metastasis [ 13, 14].
Emerging evidence supports the hypothesis that individual tumours are biologically heterogeneous and contain a minor population of cells (cancer SCs) that share the self-renewal feature of normal SCs, are responsible for sustaining the tumour and give rise to proliferating and progressively differentiating cells.
The program, sponsored by a temporary entity called the Iowa Renewal Project, featured several superstars of the Christian right as well as four possible Republican contenders for president.
The Cato Institute recently hosted a forum on the private donors' so-called "renewal" agenda, featuring Jay Schalin, the author of the Pope Center report, along with the former BB&T president John Allison and C. Bradley Thompson, the director of the BB&T-funded Institute for the Study of Clemson Universityson University.
Reform and renewal are fundamental features of every health system, though the ambition and scale of change varies over time and between countries.
The winner will have his or her proposal — for marriage or a renewal of vows — featured on a Nascar race car, the No. 99 Ford Fusion sponsored by Office Depot and driven by Carl Edwards.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com