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Simvastatin was effective both for stimulating bone morphogenetic protein-2 formation in vitro, and inducing bone formation in rodents [ 1], rendering this possibility less likely.
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This may have distracted the monkeys, even though the lack of an effect of the rotation renders this possibility unlikely.
However, several factors render this possibility improbable.
However, two considerations render this possibility unlikely.
Independent of the lack of consistency in the other transfer group (see above), experiment 4 renders this possibility unlikely, as recovery times decreased rather than increased with age in three out of four groups.
However, our findings that in situ osteoclast numbers and OCP frequency are unaffected by in vivo Pb exposure renders this possibility less likely.
Localisation, epidemiology and molecular findings render this possibility unlikely: IHC for Myogenin was negative and the MDM2 amplification is not observed in tumours of myogenic origin.
Unmeasured confounding might also help explain our findings, although our ability to control for a large number of both known and potential risk factors for CRC renders this possibility less probable.
Ovarian cancer is usually diagnosed at an advanced stage, rendering the possibility of cure unlikely.
Even if potentially Kaiser scores below the biopsy threshold may be achieved, the clinical situation of a newly diagnosed mass lesion in a postmenopausal patient warrants bioptical verification, rendering the possibility of clinical mismanagement very low.
Further, probabilities that they differed from each other were very high (P > 0.80) rendering the possibility of a type ii error very unlikely.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com