Exact(2)
However, repetitions of samples (ca. 30%) showed consistent results thus rendering the hypothesis of mis-scoring because of partial digestion unlikely.
Comparably high levels of genetic variation were estimated for all populations, rendering the hypothesis that a genetic bottleneck facilitated the emergence of the DLC-adaptive phenotype highly unlikely.
Similar(58)
To date, no reliable evidence for periodicity or Nemesis-type celestial bodies has been found, but this does not render the hypothesis obsolete; it is accepted that any large extraterrestrial body impacting the Earth's surface could and would produce climatic changes similar to those thought to have occurred around the K-T boundary.
It also renders the hypothesis of longevity controlled by programmed cell death unlikely.
Altogether, these evidences render the hypothesis of the molestus population being derived from the local pipiens form unlikely.
A significance level of P < 0.05 was adopted with no correction for multiple testings, each correlation undertaken being strongly weighted by existing evidence, thus rendering the universal null hypothesis inapplicable [ 22].
From the perspective of model testing, the important observation is that the χ test investigates whether the data is consistent with the model's/theory's constraints and claims as incorporated in the Σ matrix – which renders the tested hypothesis as notable as is the theory itself.
While essentiality was originally thought to be associated with small genomes, this notion is contradicted by the recent example of Shigella flexneri [7] rendering unlikely the hypothesis of the absence of an alternative mechanism for mRNA quality control in bacteria with reduced coding capacity.
Although such flaws rendered the cyclol hypothesis implausible, they did not make it impossible.
These inherent study design limitations render the findings hypothesis-generating and need to be confirmed in a prospective, randomized clinical trial.
The emergence of high throughput technology such as microarrays raises a fundamental statistical issue relating to testing hundreds of hypotheses thus rendering the standard P value meaningless [ 28].
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