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For example, in breast cancer cells, Tensin3 was shown to anchor integrins to the cytoskeleton, rendering the cell less motile and thereby less capable of metastasizing [9].
The prevailing model for the origins of this tumor is that a mesenchymal precursor cell undergoes a second genetic hit at one of the TSC loci, rendering the cell defective for TSC1-TSC2 complex function and, thereby, activating mTORC1.
It has been shown that when an externally repressed circuit is induced, an overshoot of transcriptional response is observed in response to steady levels of inducer, which then falls back to its pre-induction level (due to pumping out of the inducer by multi-drug efflux pumps), rendering the cell resistant to further induction [64].
Second, confirmation of KSHV infection of KS spindles is difficult to confirm without rendering the cell unviable for cytotoxicity studies.
AG1801 may elicit its effect by providing a signal, rendering the cell resistant to the induction of apoptotic injury.
These results demonstrate that the green-light induced lytic system caused partial-cell lysis, rendering the cell membranes fragile.
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However, the loss of drug effectiveness was observed due to mutations of the target cancer cells, rendering the cells resistant to the drug [4, 5].
This special DNA codes for a protein that responds to light, rendering the cells light-sensitive. .
Cell area and circularity were measured by manually rendering the cells in the phase images.
We show that HP1γ deprivation slows down the cell cycle of ESC and decreases their resistance to differentiating conditions, rendering the cells poised to differentiate.
Transfer by electric pulses is obtained when an external electric field transiently destabilises the membrane rendering the cells accessible for cDNA entry [10].
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