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The application of genetic engineering to agriculture remains controversial in the early years of the 21st century, however, rendering problematic any possible transition of agriculture from a staples to a post-staples industry.
Also, the chemical-induced destruction of endogenous beta cells is not always complete, rendering problematic the interpretation of long-term transplantation studies with exogenous islets.
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Something that until now we silently tolerated as unproblematic is rendered problematic.
Made in France was similarly rendered problematic by November's Paris attacks.
Parks's tenacity is impressive as is his inquiry and documentation of a not-so-oft rendered problematic body part.
But ESP strengthens the overall case by raising the antecedent probability of survival, insofar as it renders problematic the naturalistic view of the human person, which for most contemporaries constitutes the greatest obstacle to belief in survival.
Thus it is a commitment of a quasi-realist that normative judgments are in an important way different from most (other) paradigm descriptive judgments enough so to render problematic their status as either true or false and yet that a justification is nonetheless available for our practices of treating them as if they were in fact so.
Palmar plantar erythrodysesthesia is the usual dose-limiting toxicity of Doxil®, and it renders problematic any substantial dose escalation that liposome delivery might otherwise provide.
In his attempt to reconcile the eroticisation of lower-class men with ideals of equality and reciprocity, Symonds did not fully realise that class difference, just like age difference, rendered problematic an understanding of consensual same-sex desire.
This interpretation is rendered problematic by the fact that cyanide is an alternate substrate for yeast TST, as shown by results obtained in this study and in a previous survey of the thiosulfate cyanide sulfurtransferase activity exhibited by RHOD-containing yeast proteins.
However, this intonation of defiance of questioning the right of healthcare professionals to "tell [her] what to do"—is also rendered problematic from her current perspective: "over these last few years I'm seeing what it can do to me and pray to God I haven't left it too late".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com