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Such misfolded RNA may become a substrate for nucleases, thereby rendering it unstable.
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The modification site could not be localized possibly due to its labile property, which renders it unstable during collision-induced dissociation (CID) and higher energy collisional dissociation (HCD) activation.
Although lean hydrogen air flames are subject to thermo-diffusive effects, in this case the result is to stabilize the flame rather than to render it unstable.
The mutation of Yap1-binding domains in Amotl2a does not render it unstable.
The best explanation anyone has been able to offer is that the sheer complexity of the climate system renders it unstable — capable of flipping from one state to another.
These constraints and the fact that this model was solely based on kinetic parameters that were estimated from in vitro experiments, render it unstable in simulations of dynamic conditions.
Constitutive kinase activity of the unstable truncated mutant requires a stronger association, rendering it more susceptible to Hsp90 inhibition [ 1].
Left unconsidered was the question whether a male divinity generates certain dilemmas and tensions for the conception of masculinity, rendering its meaning unstable.
DOI: http://dx.doi.org/10.7554/eLife.03401.013 Temporal approaches to controlling populations would deliberately limit the lifetime of a suppression drive by rendering its effects evolutionarily unstable.
It has been anticipated that the truncated dystrophin induced by exons 45 55 skipping would disturb the site-responsible anchoring of nNOS, which normally binds to spectrin-like repeats 16 and 17 of the dystrophin encoded by exons 42 45 and possibly render its subsarcolemmal localization unstable [ 62, 63].
The mesoporous scaffolds come with limitations, such as storage at low relative humidity (RH) (water will replace drug rendering them unstable) and chemical reactions with acid-labile and oxidation-labile drugs.
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