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Recent report of the co-crystal structure of the MLL1 SET domain in complex with AdoHcy and an H3 peptide suggests that the lysine access channel of MLL1 SET may be widely exposed in the native protein, rendering it inefficient in aligning the ε-amine of substrate lysine with SAM for optimal catalysis [22].
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In the past, intermittent power application and MR imaging was proposed for RFA[ 18 ], but this leads to implementation problems, lengthens the procedure, and may render it more inefficient.
Finish your movie, and render it.
If in the meantime government is rendered inefficient and ineffective, so be it.
To truly isolate alertness we devised a sparse event-related design with many different randomly appearing and interleaved auditory and visual targets, thereby rendering prediction inefficient.
In a world of inhomogeneous climate policy, missing out policies on either production or consumption leaves an important policy area idle, rendering climate policy inefficient and potentially ineffective.
Our results indicate that the use of square-wave light regimes may severely skew the optimization process, rendering inefficient light use in the photobioreactor and over-estimated power inputs.
FeCl3 can be significantly employed as a coagulant for pre-treatment or post-treatment of landfill leachate having high concentration of recalcitrant compounds rendering biological processes inefficient.
As shown in both graphs, a Private-Premise deployment of web applications results in rapid cost increases, rendering such deployments inefficient.
A high level of learner control positively affected the effectiveness of instruction only with regard to intuitive knowledge, but was at the same time accompanied by large increases in learning time, thereby rendering the instruction inefficient.
Both the fat tree topology and the spanning tree based approaches suffer from the blocking of a server-to-server communications problem at high traffic, rendering the system inefficient for handling the increasing level of east-west network traffic inside of a data center.
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