Sentence examples for rendering it deficient from inspiring English sources

However, a major limitation of rAAV is its small packaging capacity (≈4.7 kb), rendering it deficient for therapies requiring large promoters and or transgenes.

The key feature of TBI is the three electron deficient imine groups, rendering it a stronger acceptor than BT.

It phosphorylates cofilin, thereby rendering it inactive.

The IUCN has listed the pigeye shark overall as Data Deficient, while noting that its rarity may render it susceptible to overfishing.

Nothing can render it false.

Finally, in our in vitro data using B. burgdorferi as a stimulus, we were not able to detect secretion of IL-1β and transcription of pro- IL-1β was reduced in Nod2 deficient cells (Figure 4A,C) rendering it unlikely that Nod2 deficiency leads to increased IL-1β secretion.

Alterations in the mechanism that promotes or inhibits the differentiation of the embryonic NPC, like p73 deficiency does, would eventually deplete the pool of embryonic NSC, rendering deficient neurogenic-niches in the adult mice.

Variant forms of MBL are very common in certain populations among healthy individuals [ 13], and it is known that alternative immune mechanisms can replace the function of MBL [ 32] thereby rendering deficient individuals immune competent.

Recently, it has been demonstrated that a defect in homologous recombination can lead to changes in drug sensitivity profile, rendering the BRCA1 deficient breast cancers sensitive to mitomycin C, cisplatin, etoposide and other drugs that produce double-stranded lesions [33].

To isolate the contribution of mRpL34 to eye development we used flies expressing an mRpL34 transgene in the Df 2R Dg248 background thus rendering the eye deficient solely in Dg [24].

Analysis of the neurogenic niches demonstrated that p73-loss depletes the number of neural-progenitor cells, rendering deficient niches in the adult mice.