Combining the models required extensive pilot work to titrate the severity of the sepsis insult such that the animals were rendered appropriately sick, reflective of sepsis, and yet still likely to have high short-term survival with antibiotics and fluid resuscitation.
And they reduce the blood count, rendering already sick people vulnerable to every available infection.
But nothing proves that if the same microorganism should chance to come into contact with some other of the thousands of animal species in the Creation, it might invade it and render it sick.
Every metropolis has a set of stereotypes linked to it, and Paris exists in many people's minds as a charming, luxurious, timeless hub of style and sophistication in fact, so many people expect the City of Light to be what they want it to be that the reality has rendered some tourists physically sick with disappointment.
Rather, by maintaining plague victims in a pestilential atmosphere and restricting the movement of the unaffected, they were positively tyrannical: It follows, no less clearly, that the continuance of persons in an air viciously disposed, must be one of the most effectual means of rendering the healthy sick, and the diseases of the sick, mortal.
A common dose of blood pressure medicine might render an already sick patient dangerously hypotensive.
But it's also a result of that mysterious thing beyond our power that can render us mentally sick or mentally well.
-- If you think you may have been exposed to a bug that will render you too sick to fly, check out specific airline waiver policies before you select a carrier, or consider purchasing an unrestricted, totally refundable ticket (These may be unaffordable but you can sometimes snag them using frequent flyer miles).
These experiments were conducted in the outbred and long-lived white Dahomey genetic background, where the null mutation for 4E-BP itself reduced lifespan only moderately, and the previous failure to extend lifespan by rapamycin in this mutant may have been because the genetic background used rendered the mutant too generally sick to respond to the drug.
More important, the voucher system would pay insurers part of their cost as a lump sum and part as a reimbursement fee for actual services rendered, reducing the incentive for insurers to avoid sick patients.
