rendered non-functional

USAGE SUMMARY

The phrase "rendered non-functional" is correct and usable in written English.
It can be used to describe something that has been made inoperative or ineffective, often in a technical or mechanical context. Example: "After the power surge, the equipment was rendered non-functional and required immediate repair."

✓ Grammatically correct

Science

News & Media

Human-verified examples from authoritative sources

Exact Expressions

23 human-written examples

Firstly, the tyrosine phosphorylation of Gab1 is drastically reduced in mouse embryonic fibroblasts (MEFs) lacking Grb2 or expressing a functionally impaired Grb2 protein in which its SH2 domain has been rendered non-functional by the E89K knock-in mutation [ 60].

Cell Communication and Signaling

Recent research (notably cross-species comparisons of gene sequences rendered non-functional by mutations) has greatly strengthened the case that humans and chimpanzees share a common ancestor.

The Economist

At those loci, we identify candidate genes which, when rendered non-functional, alter those very demographic properties, and in turn, we identify candidate coding or regulatory variants that alter protein structure or gene expression, respectively, being prospective contributors to the variation in phenotype.

Progress in Retinal and Eye Research

Most loci are rendered non-functional by mutations, but several intact retroviral genes are known in mammalian genomes.

Plosone

These findings show that the Nts-1 receptor is rapidly rendered non-functional after 15 minutes at a restrictive temperature.

Plosone

Following either tandem or segmental duplication events, one of the duplicated genes can be rendered non-functional via the accumulation of deleterious mutations [6].

Plosone

Human-verified similar examples from authoritative sources

Similar Expressions

37 human-written examples

The aim of the present study was to unravel the functional role of Kv10.1 in the brain by generating knockout mice, where the voltage sensor and pore region of Kv10.1 were removed to render non-functional proteins through deletion of exon 7 of the KCNH1 gene using the '3 Lox P strategy'.

Human Molecular Genetics

Through re-directing the normal pre-mRNA splicing process, AOs could potentially generate non-functional transcripts by targeted excision of a frameshifting exon that would then render the induced transcript susceptible to degradation through the nonsense-mediated decay pathway [21].

Molecular and Cellular Pediatrics

Of course this is true assuming that UKA is well balanced with equal flexion and extension gaps, otherwise it may happen that ACL loses its physiological strain, thus rendering it non-functional.

Journal of Orthopaedics and Traumatology

Deletions of exons 2, 4 and 5 remove much of the extracellular and transmembrane domains of the protein and are therefore likely to render it non-functional.

Plosone

The transposase gene is mutated in ISPfr8: a guanidine insertion created a frameshift observed in all three copies rendering it non-functional.

Plosone

Expert writing Tips

Best practice

Use "rendered non-functional" to clearly and concisely describe a state where something is no longer working as intended, especially in technical or scientific contexts.

Common error

Avoid using "rendered non-functional" in casual conversations or informal writing. Simpler phrases like "stopped working" or "broken" are more appropriate.

Linguistic Context

The phrase "rendered non-functional" typically functions as a predicate adjective, describing the state of a noun after it has been made unable to perform its intended function. As Ludwig AI confirms, it accurately conveys this meaning across varied contexts.

Expression frequency: Common

Frequent in

Science

87%

News & Media

9%

Formal & Business

4%

Less common in

Academia

0%

Encyclopedias

0%

Wiki

0%

Ludwig's WRAP-UP

In summary, the phrase "rendered non-functional" is a grammatically correct and commonly used expression, particularly in scientific and technical fields, to describe something that has been made inoperative or ineffective. Ludwig AI confirms its accurate usage. While simpler alternatives exist, this phrase provides a level of precision often required in formal contexts. It's best practice to avoid using it in casual conversation, where simpler terms would suffice. This detailed analysis offers a comprehensive understanding of the phrase's usage, alternatives, and appropriate contexts.

More alternative expressions

Phrases that express similar concepts, ordered by semantic similarity:

made inoperative

Replaces "rendered" with "made", which is a more direct verb, slightly changing the tone.

became non-functional

Changes "rendered" to "became", focusing on the change of state rather than the action causing it.

ceased to function

Replaces the entire phrase with a more formal and concise alternative.

became inoperative

Substitutes "non-functional" with its synonym "inoperative".

rendered unusable

Replaces "non-functional" with "unusable", indicating that something cannot be used for its intended purpose.

made dysfunctional

Replaces "non-functional" with "dysfunctional", suggesting impaired function.

brought to a standstill

Uses an idiomatic expression to convey the idea of something stopping working.

rendered ineffective

Replaces "non-functional" with "ineffective", focusing on the lack of desired effect.

put out of action

Uses a more informal, action-oriented phrase to convey the same meaning.

rendered inactive

Substitutes "non-functional" with "inactive", implying a state of dormancy or lack of activity.

FAQs

What does "rendered non-functional" mean?

It means something has been made unable to perform its intended function. Similar phrases include "made inoperative" or "became inoperative".

When is it appropriate to use "rendered non-functional"?

This phrase is suitable in technical, scientific, or formal contexts where precise language is important. It's often used to describe the state of equipment, systems, or biological components.

Are there simpler alternatives to "rendered non-functional"?

Yes, depending on the context, you could use phrases like "stopped working", "broken", or "out of order". However, these may lack the precision of the original phrase.

What's the difference between "rendered non-functional" and "became non-functional"?

"Rendered non-functional" implies an action caused the state, while "became non-functional" simply describes a change of state without specifying the cause. The former is active, while the latter is passive.