Sentence examples for rendered defective from inspiring English sources

Biologists name genes inversely, some would say perversely, by describing what the organism cannot do after one of its genes has been rendered defective with a mutation.

Implication: Even when LRRK2 itself isn't rendered defective by a mutation, anything impairing this protein's ability to complex with faulty mitochondria's molecular anchor produces the same result -- a hugely stressed nerve cell that's much more susceptible to biting the dust.

To test this hypothesis, we examined the release of HCV Core into culture supernatants from cells rendered defective for ESCRT components by RNA interference.

However, the capacity of eIF3 to stimulate termination-reinitiation, particularly from a defective TURBS, was confirmed, including a TURBS rendered defective through a point mutation in motif 1. Together, these data support the view that efficient termination-reinitiation requires both mRNA-rRNA interactions and the participation of eIF3.

PICs that form with TFIIB R66E are rendered defective prior to pol II CTD serine 5 phosphorylation.

We thus generated psd1Δ and psd2Δ strains, which are additionally rendered defective for respiration owing to loss of mitochondrial DNA (Rho).

This rendered the defective equipment unused when major services and repairs were required as testified by one of the respondents: "It took eight months for the technical service providers to come and they never came on time " (Key Informant, Regional Hospital).

Ad-based vaccines are particularly attractive gene vehicles as they can stably express large foreign inserts (∼10 kbp), they remain epichromosomal and can be easily rendered replication defective by deletion of the E1 locus [80,87].

Herein we describe an innovative vaccinia virus (VACV -derived VACV -derivedorm technology termed Sementis Copenhagen vaccine(SCV), which was rendered multiplatformn-defectechnologyrgetermedletion of the eSementis viral assembly gene D13L.

Knocking down such genes not only blocks autophagy but also renders apoptosis defective, making the interpretation of autophagic roles unreliable.

That need not render it defective as an account of political obligation, but it does entail that we should not take the phrase "political obligation" to be synonymous with the phrase "a duty to obey the law simpliciter," but only with the phrase "a citizen's (or member's) duty to obey the law".