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The low proportions of P in phytic acid in plant leaves render the finding of considerably higher levels of phytic acid in foliage of epiphytic bromeliads (>20 % of total P; Winkler and Zotz 2009; U. Winkler, unpubl. res).
However, it is argued here that based on the cost-benefit analysis of traits and the concepts from BRN, it should be possible to make a-priori predictions about pattern of behaviour and, as such, render the finding as not counter-intuitive.
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14 15 16 17 If present, industry sponsorship bias may render the findings of such comparative assessments invalid.
Nevertheless, there are two important aspects designed into the current study that render the findings relevant and interpretable.
Maslanyj et al (2009) have shown that 'exposure misclassification render the findings from studies that rely on distance alone uninterpretable'.
These inherent study design limitations render the findings hypothesis-generating and need to be confirmed in a prospective, randomized clinical trial.
Strengths of the present study include its liberal eligibility criteria and naturalistic treatment setting, which should render the findings generalizable to wide populations of patients with schizophrenia seen in usual outpatient settings [ 22].
Although such data provide valuable insights on formaldehyde and potential interactive effects with other irritant chemicals, the documented respiratory differences between rats (obligatory nose breathers) and humans (oronasal breathing) render the findings from such studies of limited relevance.
8 By contrast, in pragmatic trials, as in the real-world delivery of care, blinding of participants and healthcare providers are sometimes considered not necessary, so as to render the findings more applicable to usual care setting.
Biologically, as a result of junctional recombination, P/N nucleotide editing and somatic hypermutation (for BCR/antibodies) [ 14], the protein sequence space of CDR3s is immense and renders the finding of significant overlap between repertoires highly unlikely.
Several GWA studies have received criticism for omitting important quality control steps, rendering the findings invalid, but modern publications address these issues.
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