Guo et al. also generated a second line of mice carrying a mutation in ALK7 that does not affect its function, but renders it sensitive to inhibition by a custom-made chemical.
Model over-fitting refers to the case when a model is too complex, that renders it sensitive to small changes in observation statistics [19,20,23,29].
It is possible that Oithona might have evolved a prey avoidance strategy when alternative diets are available, rendering it sensitive to even moderately low PST production.
Thus, HSP90 is key to maintaining the responsive plasticity of the defense system; reduction of HSP90 function predisposes the plant to herbivore defense but renders it sensitive to pathogen attack.
BJx109 replicates poorly and does not induce weight loss or disease in mice (Fig. 1) and the HA of BJx109 is highly glycosylated, rendering it sensitive to destruction by components of the innate immune system, including collectins [28], [29] and airway macrophages [30], [31].
The combinatorial nature of LAD renders it sensitive to a large number of variables, just as other algorithms, such as decision trees.
The requirement of having to learn complex relationships of extra-maze visual cues is the aspect of the test that renders it sensitive to hippocampal dysfunction.
We hypothesize that the temperature-sensitive mutation in the RNA-binding domain of FOG-1 renders it sensitive to the ribonucleoprotein (RNP) assembly defects resulting from inefficient splicing activity.
Remember, this rule has two ways to enforce stability: Either 〈 δ〉 = 0 or x0 = 0, which makes this rule a strange chimera between TD and ISO, also rendering it sensitive to the numerical auto-correlation problems.
Recent modifications to the method render it less sensitive to assumption but the modified method remains sensitive to the assumption that exposure is not event dependent in the case of hip fracture and TZDs this assumption cannot be made; TZD exposure is less likely once fracture has occurred [ 23].
