The phrase "render it difficult" is correct and usable in written English.
You can use it when describing a situation or action that makes something challenging or hard to accomplish.
Example: "The lack of clear communication can render it difficult for the team to meet deadlines."
Alternatives: "make it challenging" or "create obstacles."
Both the complex genotype and its heterogeneity render it difficult to determine which genomic alterations are important in osteosarcomagenesis, as not all alterations may lead to a difference in mRNA, protein levels, or enzyme activity in the tumor tissue.
Comparison with the Bayesian method STRUCTURE confirmed the usefulness of both approaches and emphasized the reliability of network analysis to unravel and study hybridization Speciation is a central process in evolution, but its complexity and duration render it difficult or impossible to observe and study as a whole.
Recent clinical studies reporting the high frequency of inadequate chest compression depth (<38 mm) during CPR, have prompted the question if adult human chest characteristics render it difficult to attain the recommended compression depth in certain patients.
This results mainly from the very large density variations of supercritical-pressure water in the core, which render it difficult to ensure reliable values for parameters such as power peaking factors and reactivity worths.
The discrepancies in findings of theoretically similar constructs render it difficult to make meaningful conclusions regarding the nature of impulsivity.
In addition, the fixed values selected at high SNR region (≥2.8 dB) render it difficult to achieve the joint iterative decoding gain since the values are too small.
Hindustani is widely recognized as India's most common lingua franca, but its status as a vernacular renders it difficult to measure precisely its number of speakers.
Sontag didn't quite define standards for judging camp; she emphasized that its protean nature renders it difficult to evaluate.
Glioblastoma multiforme (GBM) is the most common primary central nervous system malignancy and its unique invasiveness renders it difficult to treat.
The problem with NP600, however, is that it was larger in amplitude to targets than pseudo-targets at prefrontal sites, rendering it difficult to fully understand its functional meaning.
Blockchain technology enforces a distributed consensus and cryptographic transactions, rendering it difficult to compromise the integrity of its records without being noticed by an entire network.
