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One option is that newly emerging edges cancel out disappearing edges (equilibrium state), which is biologically costly by removing already established connections and unlikely because new connections are established mostly early in the development.
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However, if removed, already established NIS can be used as bioremediators, having a positive effect on different ecosystems.
As a final step, these variants were screened against the control group and were removed unless already established as a deafness-associated damaging mutation.
To test the involvement of the oncogenic signal, we removed Ras expression from already established OIS cells.
Nobody is proposing to remove earthworms where they are already established.
However, if the cancer is already established and has spread to the lymph nodes and lungs, then major surgery to remove the primary lump would be inappropriate.
That right was already established.
The brand is already established in Asia.
The right to differ was already established.
I'm already established as a persona.
She is already established in her field.
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