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These data sets were made progressively sparser by removing activity records and the models re-learnt.
To explore this issue, we have used two complete data sets to simulate sparseness by removing activity labels progressively.
By removing activity of the two known regulators mcbR and ssuR in both mutants, only CysR-dependent regulation should remain.
The difference in adenine removing activity between the p.Y151C protein and p.G368D protein may be related to the difference in clinical phenotype.
For instance, it is well established that the oxidative DNA lesion 8-oxoguanine is mutagenic and that hOGG1 represents the major 8oxoG removing activity in human cells.
The results revealed that the p.V47E, p.R281C, p.A345V, and p.S487F proteins largely retain adenine removing activity, but that the adenine removing activity of the p.I195V protein is mildly impaired and the activity of the p.Y151C, p.R154H, p.M255V, p.L360P, p.G368D, p.P377L, p.452delE, p.R69X, and p.Q310X proteins is severely impaired.
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In managing building design, the use of lean management tools can be seen a driver increasing value to the customer, improving operations and removing activities that do not add value.
The radionuclides removing activities of the following treatments show a homogeneous trend, with a decreasing tendency line reported in Figure 3.
Performance is higher in the label removal model, where the removed activity labels might be compensated by activity values of the same compound on related assays.
In contrast, the H498A/R637A mutations, located in the putative peptide-binding groove immediately adjacent to the active site, not only remove activity towards TAB1 but also abrogate self-glycosylation.
Excluding voxels responding to scrambled images from the Hexe map further removes activity in low-level visual areas.
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CEO of Professional Science Editing for Scientists @ prosciediting.com