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Next, we removed systematic errors included in these interferograms, following the method given by Fukushima and Hooper (2011) with some modifications.
We therefore conducted a robustness analysis that removed systematic differences between observers.
We removed systematic bias in the data by applying lowess (smoother span 2/3) [ 25] and dye-swap normalisations to have the least possible information loss.
Pre-processing adjusted for non-specific binding and background noise, whereas normalization removed systematic variation in the data due to effects other than biological differences.
In particular we observed that DWD, a popular method used in a number of previous studies, removed systematic bias at the expense of genuine biological variability, potentially reducing legitimate biological differences from integrated datasets.
The complex appears to be in equilibrium between the octameric state and a state of free Pep2 and free TreS tetramer, as including free Pep2 in the model removed systematic deviations between data and fit.
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Between-array normalization aims at removing systematic effects occurring between arrays, e.g. when one array yields systematically higher expression values than a second one even though hybridized with the same sample.
The most important task of the decennial census is in updating annual population estimates for small areas to remove systematic bias so that a huge number of studies and also funding calculations can be enacted.
By removing systematic differences across treatment groups, simple randomization is assumed to protect against bias.
The data were transformed and double referenced to remove systematic deviations seen in the binding responses.
To remove systematic errors in the model simulation originating from structural and parametric errors, a parsimonious bias correction procedure is incorporated into the observation equation.
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