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EVER since NewSouth Books announced it would publish a version of "The Adventures of Huckleberry Finn" with the "n-word" removed, reaction has split between traditionalists outraged at censorship and those who feel this might be a way to get teenagers, especially African-American boys, comfortable reading a literary classic.
Essentiality of zero indicates that the removed reaction has no effects on the cell growth rate, while essentiality of one means complete stoppage of the cell growth rate for the removed reaction.
With these largest deviations removed, reaction times larger and smaller than 2* the remaining SD from the mean were deleted.
For each removed reaction in the metabolic network of a given endosymbiont, we checked that the concerned metabolites were not a product or a source of the metabolism of the other endosymbiont.
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Removed reactions in the metabolic network of Portiera.
Here, 200 individuals were used per population and the initial population was seeded randomly using between two and six removed reactions.
In addition, we removed reactions which produce compounds that were not observed in Paenibacillus and were only present in single reactions.
In these two examples, mCADRE correctly removed reactions for which many other reactions with little expression evidence are needed to carry flux.
To derive hepEFM, we first removed reactions that either produce or consume an extracellular metabolite from the network, resulting in a graph comprising 1,418 reaction nodes.
To do this, we removed reactions which were unlikely to take place in these organisms, or which did not interest us in the case of this work.
For example, the OptKnock [ 2] algorithm removed reactions from a FBA model to design a strain of E. coli with optimal production of a metabolic byproduct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com