We have shown here that, compared to simply ranking the poses output by the docking program according to a single docking score, an initial filtering of the docked poses with a pharmacophore query to remove poses that do not form certain essential interactions with the target binding site greatly improves the quality of the results.
On Monday, Gov. James E. McGreevey announced that anthrax spores had been found in a mailbox on Nassau Street, Princeton's main thoroughfare, but that the box had been removed and posed no danger to the public.
But removing them poses logistical, financial and public safety risks.
His presence alone was clearly an inspiration, though: Lancashire, through Buttler and Prince in particular, racked up 229 for four, their highest-ever T20 score, and with two balls to go Flintoff stood up, removed his pads, posed with a couple of excited kids taking selfies and headed up the stairs of the Graeme Hick Pavilion.
In red socks, fringed suède moccasins, and — from his G-Star clineing line — a hoodie printed with a photograph of the interior of a Concorde and a pair of spent cargo pants ("I'm going to have to have them surgically removed soon"), Newson posed a contradiction: a mellow nomad fuelled by a flinty testosteronal intensity.
To remove the danger posed by jihadi terrorism, abstract arguments are not enough; we need a strategy for defeating it.
He said that if the measures already planned did not remove the risks posed by large banks, "additional steps would be appropriate".
Ankara is in a dilemma: it wants to remove the threat posed by Isis on its border but is concerned that a consequence of this will be to help keep the Syrian president, Bashar al-Assad, in power.
The refusal by the Supreme Court to revisit the matter, after two lower courts approved the sale, removes the uncertainty posed by a decision by Justice Ruth Bader Ginsburg on Monday to halt the deal temporarily pending further review.
Furthermore, a détente with Tehran would likely remove the threat posed by Hezbollah in southern Lebanon, which acts as a deterrent against possible Israeli military action on Iran, much like Israel's nuclear submarines act as a deterrent against Iran in the Persian Gulf.
