Overall, we discovered that half the genome, i.e., bp 3669 11,398, could be removed with no significant change in the phylogeny (pAU = 0.077) while still maintaining overlap of TMRCA 95% credible intervals.
However, reanalysis of the data with non-seizure free patients removed made no significant differences to either the functional MRI or the behavioural results.
The estimated interindividual variability was small for the transformation factor, CL/ F, Q2/ F, and VC/ F, and could, therefore, be removed with no significant impact in the final model (ΔOFV = 2.40).
For HLMrefined, we identified and removed any significant linear trend in historical data.
Hennerbichler et al. have shown in an experimental setup, that punch defects, which were directly filled with the removed punches, showed no significant difference in healing potential between the vascularized and avascularized meniscus zone (Hennerbichler et al. [2007]).
When size was removed, there was no significant relationship between taxonomic rank and similarity in integration across all australodelphian marsupials, although average similarity of integration slightly increased from infraclass (0.53), to order (0.55) to family (0.60), and to genus (0.61).
With sodium valproate (median improvement 62.5%% (IQR = 21.1 %)) an apparent trend in the data is driven by an outlier (visible on the bottom left), and when this is removed, there is no significant dose response effect or interaction between drug doses and response.
However, when the cells were incubated for only 30 min with free FUdR and then washed to remove extracellular FUdR, no significant growth inhibition was detected during subsequent culture (Table 1).
The data were clustered using Cluster 3.0 (De Hoon et al. 2004); prior to clustering, data were filtered to remove barcodes with no significant change across any time point (all log2 values < 1) or to include only those with significant change in 50% of experiments.
