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The evidence that the isolated regulatory domain will bind phenylalanine and the loss of allosteric properties when the regulatory domain is removed establish the regulatory domain as the likely site for the activating allosteric site.
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Plant genetic engineering has the potential to both introduce new allergenic proteins into foods and remove established allergens.
One frequently invoked explanation for this diversity is disturbance, which removes established trees and creates habitat for early successional species (White and Jentsch 2001).
This may reflect the fact that deletions require removing established segments of protein sequence.
HAMLET thus offers a new approach to colon cancer treatment, acting by removing established tumour cells and preventing tumour development in the intestinal mucosa.
In other study Zanatta et al. reported little antiplaque and antigingivitis effect of CHX mouthrinse on previously plaque covered surfaces and pointed out to the importance of removing established biofilm before CHX usage [ 47].
The further evaluation of the phenomenon of de-masking by removing established ADR-drug associations from the background, as others have both hypothesized and performed [ 29, 30], could be another way of improving the screening performance.
Therefore, these results suggest that AGEs accumulation might play a considerable role in the diabetic nephropathy and it is likely that inhibiting the formation of AGEs or removing established AGEs modifications will form an important component part of future therapy in patients with diabetes, acting in concert with conventional approaches to prevent diabetic renal injury.
The nanowire template functions as a sacrificial core which was later removed to establish the central opening through the nanotube.
After 2 h of ischemia the nylon filament was carefully removed to establish reperfusion.
Subsequently, the dilators were removed to establish a tubular operative corridor.
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