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Patients were then placed in a posterior splint and encouraged to remove the splint to perform gentle passive and active range-of-motion exercises 3 5 times per day.
Only 10 patients were told to remove the splint themselves after 3 weeks with no appointment scheduled (table 6).
This may have been due to the fact that there was no minimum wear-time specified, so patients were able to remove the splint and exercise their joints as they saw fit to prevent stiffness.
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However, the requirement for a splint to bring the 5' and 3' ends together increases the cost of DNA synthesis and requires an additional step to remove the splints after circularization.
Finally, it should be noted that patients that received transverse expansion during surgery required a 4 6 weeks waiting period before removing the splint prior to starting orthodontic treatment.
We removed the splint by treatment with T7 exonuclease.
This method was simpler and did not require removing the splint DNA.
If the patient had post-wear discomfort or stiffness lasting more than one hour after removing the splint, the duration of the treatment was then reduced for the next two scheduled stretching bouts.
For the next week, Paterson visited her every morning, discovering each time that she had removed the splints he'd applied the day before.
The plaster splint was applied for two postoperative weeks until sutures were removed, when the splint was replaced with a non-weight-bearing cast boot.
Splint therapy can also decrease loading of the TMJ and remove the triggering mechanisms that program the neuromuscular system to maintain the mandible in an abnormal position [12 15].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com