Exact(2)
Base quality score recalibration optimized to SOLiD 5500xl was used to remove reference bias.
One may remove reference bias before the analysis by masking SNPs in the reference genome during the alignment or by aligning reads to a diploid personal genome.
Similar(58)
We created an allelic imbalance detection pipeline, AA-ALIGNER, to remove reference mapping biases influencing allelic imbalance detection and evaluate accuracy of allelic imbalance predictions in the absence of complete genotype data.
To correct errors in the assembly and remove any reference bias, we aligned the reads for each strain back to its assembly.
Second, to address the two concerns while removing any reference bias, we mapped all species against the de novo assembly of N. paniculata, using a TE database based only on insertions identified in A. thaliana and A. lyrata.
We have removed reference to cBIOPortal in the revised manuscript.
As shown by [ 31], even if the reference bias is removed (e.g., by masking SNPs in the reference genome), the inherent bias still exists.
Therefore, regardless of whether the reference bias has been removed from the data in the preprocessing or not, the iASeq model is able to automatically handle it and adjust the inference accordingly.
Reference bias.
What about reference bias?
This results in a systematic bias, called the reference bias.
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