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As mutations arise in the genome, selection acts to remove deleterious mutations segregating within natural populations.
Clonal selection will remove deleterious and favor beneficial somatic mutations [ 45].
This transfer can spread advantageous variation and remove deleterious mutations [ 9, 10].
Therefore, it is possible that Pif1's periodic patrolling activity contributes to the cell's ability to remove deleterious R-loops.
Selection can fix beneficial and remove deleterious recessive mutations more effectively on the X (Charlesworth et al. 1987; Rice 1984).
Genome replacement is an effective method to remove deleterious mutations that may accumulate in a specific genome and/or to acquire advantageous genes.
Similar(45)
We recommend (1) including this classification in conservation planning, (2) removing deleterious structures from high-priority sites, and (3) assessing efficiency and use of this classification scheme elsewhere.
The hepatic ASGPR system is proposed to be responsible for removing deleterious glycoconjugates from the circulation.
Purifying selection due to functional constraints limits variation in coding regions by removing deleterious mutations.
In larger sized populations, sexual selection may be involved in removing deleterious recessive alleles [ 14, 15].
The effective size of a population (N e) impacts how effectively selection removes deleterious mutations and fixes advantageous mutations.
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