In each hybridisation round some cDNA was removed indicating removal of non-regulated genes (data not shown).
As far as we know, Def1 represents the first example of a protein in which nuclear accumulation occurs as a result of regulated, proteolytic removal of a domain that directs cytoplasmic transport.
Via the PDZ domain, PICK1 interacts directly with AMPA receptor subunits and is involved in the regulated removal of AMPA receptors from the synaptic plasma membrane.
We show that this is due to increased bile acid metabolism and up-regulated removal of LDL, even though TCPOBOP increased cholesterol synthesis under conditions of hyperlipidemia.
Often the process of regulated harvesting begins with the removal of a few eggs, juveniles, or adults from wild populations.
In contrast to inflammatory genes such as VCAM-1 and SELE, which were rapidly down-regulated upon removal of IL-1β (Fig 2A), miR-146a/b remained elevated for more than 2 days (Fig 2B).
Removal of the cap (decapping) is a regulated process catalyzed by at least two Nudix hydrolase enzymes, Dcp2 and Nudt16, which release mGDP (mGpp) and 5′-end-monophosphorylated RNA (pRNA).
It's time for President Obama to break the silence of the growing coalfield crisis, from underground mining disasters to the strip-mining and mountaintop removal disasters, and take immediate and urgent action to end two centuries of regulated manslaughter in the coalfields, and bring coalfield outlaws to justice.
In truth, mountaintop removal operations have been plundering central Appalachian since 1970 -- more than four decades of regulated criminal violations, civil rights abuse, and death.
Table 3 shows DAVID gene ontology (GO) analysis for the top 50 up-regulated genes following removal of the mouse cross-hybridizing probes.
