On the other hand, a study in C. elegans has shown that kri-1, the worm ortholog of KRIT1/CCM1, is required for germline removal-dependent life span extension through regulation of DAF-16, the worm ortholog of mammalian FoxO genes [27].
Consistently, a seminal study in C. elegans [27], reporting that a functional connection between kri-1, the worm ortholog of KRIT1, and DAF-16, the worm ortholog of mammalian FoxO genes, is required for germline removal-dependent life span extension, has demonstrated that KRI-1 function is dispensable when DAF-16 is unphosphorylated on Akt-consensus sites.
The regulation of FoxO by KRIT1 has been also demonstrated in C. elegans, where kri-1, the worm orthologue of KRIT1/CCM1, is required for germline removal-dependent lifespan extension through regulation of DAF-16, the worm orthologue of mammalian FoxO genes [115].
We reported that while not repaired, UVC-induced mtDNA damage is slowly removed in C. elegans, and that this removal is dependent on genes coding for proteins involved in mitochondrial fusion, fission, and autophagy.
The null hypothesis was that newer HF or HE dialysis membranes removed iron in clinically significant amounts and that the removal was dependent of UFR.
When the residence time was long enough, the eventual Hg removal was dependent on the thermal decomposition temperature.
Ease of implant removal is dependent on the stem design, geometry, and location/extent of porous ingrowth surface.
The pH, adsorbent dose, initial dye concentration, time and temperature are chosen as the independent input variables and the efficiency of dye removal as dependent response variable.
In the batch adsorption technique studied, the ion removal was dependent on the adsorption time, metal ion concentration, adsorbent amount and pH of solution.
