Sentence examples for remote tissue from inspiring English sources
In conclusion, these findings demonstrate that may PF4 represent an important mediator of local and remote tissue damage.
The role of platelet factor 4 in local and remote tissue damage in a mouse model of mesenteric ischemia/reperfusion injury.
During tourniquet induced ischemic reperfusion, reactive oxygen species and cytokines appear and cause cellular damage and remote tissue injury.
These studies were designed to determine whether the cytokines responsible for remote tissue injury are also synthesized and accumulate in the ischemic or reperfused hind limb.
In Ptx3−/− mice, local and remote tissue injury was inhibited, and there were decreased nuclear factor-κB translocation and cytokine production.
We show that a deficiency in PF4 protects mice from local and remote tissue damage after 30 minutes of mesenteric ischemia and 3 hours of reperfusion in PF4-/ mice compared to control B6 mice.
Open Abdominal Aortic Aneurysm (AAA) repair necessitates the use of an aortic cross-clamp which causes an ischaemia-reperfusion injury to remote tissues which can lead to multiple organ dysfunction syndrome (MODS) including acute lung injury (ALI) and death [1].
However, xenobiotic reaction can happen locally (Böstman et al. 1990; Böstman 1992), and the effect of localized application of these reagents in the abdominal cavity, i.e., the potential adverse effects on normal tissues in the vicinity of the treatment site or remote tissues to which the reagent has spread, have not been examined.
The fetal inflammatory response to certain cues such as lipopolysaccharides (LPS) [31] can be detected not only in the brain and the lung but also in remote tissues not directly exposed to LPS such as the spleen, liver, and mediastinal lymph nodes [32 34].
However, the deletion greatly impaired the ability of B. burgdorferi to disseminate to remote tissues after inoculation into mice.
B. burgdorferi producing OspC with 5-AA deletion disseminated to remote tissues, especially to the heart and ear at a remarkably slow pace in immunodeficient mice.
