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Although it seems that CCN2 is not a good circulating biomarker, we cannot exclude that locally released CCN2 in the myocardial tissue plays an important role in fibrosis and in the remodelling process of the infarcted myocardium.
6 However, recent studies have indicated that inflammation, necrosis and fibrosis play roles in the structural remodelling process of the atria, contributing to the perpetuation or recurrence of AF.
Osteoarthritic changes are primarily the result of a disturbance in the remodelling process of joint tissues resulting from the failure of cells to maintain a homeostatic balance between synthesis and degradation; as the disease advances, the catabolic process exceeds the anabolic one, leading to progressive joint tissue lesions.
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Their presence more likely indicates cellular remodelling processes of hitherto unknown significance.
During the remodelling processes of the endosteal bony callus the amounts of newly formed bone increased between day 28 and 49.
Osteoarthritic changes are primarily the result of a disturbance in the remodelling processes of tissues resulting from the failure of cells to maintain a homeostatic balance; as the disease advances, the catabolic process exceeds the anabolic ones leading to progressive joint tissue lesions.
Mechanical stress affects the healing and remodeling process of ACL after surgery in important ways.
It forms around a framework of collagen fibres and is eventually replaced by mature bone in a remodeling process of bone resorption and new bone formation that creates the osteons.
When implanted in rabbit bone critical defects, a remodeling process of the gallium-doped implant started and an excellent bone interface was observed.
The purpose of this experimental study was to investigate the long-term biocompatibility as well as the integration in the remodeling process of a new polymer of this group of substances that was used for both fragment adaptation and implant fixation in a large-scale animal model.
The diminished forces cause the remodeling process of bone growth, which circumferentially reduces the cortical bone thickness.
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CEO of Professional Science Editing for Scientists @ prosciediting.com