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The distance of the fracture from the end of the bone is also considered when evaluating the remodeling ability of the bone.
The periosteum in children is thick and promotes faster healing of the fracture, as well as increased potential for remodeling ability (Figure 2).
Its nucleosomal remodeling ability is the highest of the SWI2/SNF2 type ATPases [25] and it is the most active HDAC activity found in Xenopus and mammalian cells.
The key to activate BIN1 membrane remodeling ability is to dissociate the exon10 SH3 mediated inhibitory complex.
It appears that colonies under LIF/serum conditions have an increased dynamical remodeling ability.
This plasticity is a crucial morphological characteristic of the ER and the remodeling ability seems to be correlated with the diversity of its functions.
In the mid-/long-term, however, remodeling abilities are required to sustain somatic ingrowth in children or, in general, to operate reparative processes.
CSB is a member of the SNF2/SWI2 family of DNA-dependent ATPases (Troelstra et al. 1990) and is suggested to have chromatin remodeling abilities, possibly through recruitment of the p300 histone acetyltransferase (Citterio et al. 2000; Newman et al. 2006; Frontini and Proietti-De-Santis 2009).
In addition, it has been demonstrated that also the PNPLA3 I148M variant by altering lipid droplets remodelling impairs the ability to export triglycerides to secreted VLDL [ 45, 46].
Binding of u-PA to its receptor facilitates direct plasmin-mediated proteolysis and indirect activation of additional protease systems such as matrix metalloproteases thereby serving to increase the tissue-remodelling ability and invasion capacity of carcinoma cells (Sidenius and Blasi, 2003).
With all the prospects for a life-long durability and abilities of remodelling and adaptation, tissue-guided regenerated valvular conduits could drastically reduce the number of reinterventions and hence the health system costs for heart valve disease management.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com