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Likewise, another study showed that patients who were in remission at 6 months continued to be in remission 1 year later despite the fact that they had abandoned treatment [33].
Two definitions were used, in separate analyses, for YMRS remission: (1) a YMRS Total score of <12 at endpoint (Day 21); (2) a YMRS Total score of <8 at endpoint (Day 21).
Such resurgence could occur even twenty years after remission (1, 2).
Two mice on the combination regimen relapsed and achieved a second remission after a single dose of CD19L sTRAIL + TBI (Mouse #1: Remission 1: 19 days, Remission 2: 13 days; Mouse #2: Remission 1: 18 days, Remission 2: 12 days).
Survival analysis performed separately for each remission criterion demonstrated that < 50% of subjects remained in remission 1 year later.
Indeed, if infection with one of these microorganisms triggers an exuberant granulomatous immune response, the 50 80% of patients who usually have a spontaneous remission 1 likely clear the offending organism and the immune reaction subsides.
Similar(38)
Approximately two-thirds of patients treated with splenectomy achieve a sustained remission [ 1, 5, 9].
Other previous studies found that IBD patients with active disease status are more likely to have anemia than those being in remission [ 1, 11, 18].
However, patients may still experience radiographic progression of bone erosions, despite being judged to be in clinical remission [ 1, 3, 4].
However, there has been a paradigm shift in RA therapy during the past decades: current treatment aims at persistent and complete disease suppression, resulting in remission [ 1, 3, 4].
Experts in depression treatment have gained insights into how disabling and costly MDD is and how important it is to treat depressed patients to full remission [ 1, 22, 23].
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