Indeed, a recent report [ 42] has shown that even when a marker gene (GFP) is integrated into the T. cruzi genome under the control of a strong constitutive rRNA promoter, the FACS profile of a stably transformed cell line is remarkably heterogeneous, with approximately 25 30% of cells expressing little or no detectable GFP at a given time.
Remarkably, over-expression of eIF6, both in stably and transiently transfected cell lines, had little or no effect on cell proliferation but markedly increased cell migration and invasion, suggesting that eIF6 could be an important downstream effector whereby Notch-1 modulates cell motility in physiological or pathological conditions.
The remarkably well dispersed spectrum indicates that the PD remains stably folded, even at pH of 3.5.
However, and remarkably so, there are two s100 gene pairs, which are stably linked in the teleost genome, whenever present in the same species, albeit not closely related phylogenetically (S100A10a/S100I and S100A11/S100S, cf. Figure 6 and Additional File 2).
Remarkably, PR-dependent gene expression profiles obtained from T47D cells stably expressing PR (assayed using the Illumina platform) were significantly similar to gene array data obtained from the same parental cells (T47D) inducibly expressing PR (assayed via the Affymetrix platform; see Additional file 2).
Indeed, by conventional time-lapse FLM experiments we found that even after the Z-ring has stably assembled at the midcell, the Z-ring is still remarkably dynamic the midcell band sometimes split in two, was oriented at an angle or appeared helical despite limited spatial resolution (Figure S4).
Remarkably, over-expression of α-SNAP enhanced SOCE beyond what is typically seen in cells stably co-expressing Stim1 and Orai1.
Live-cell imaging performed on HeLa cells stably expressing histone H2B green fluorescent protein (GFP) showed that all three siRNA treatments also caused remarkably similar mitotic phenotypes.
Remarkably, the absence of both Myb and Mip130, or of both Myb and E2F2, caused variegated expression in which high or low levels of Polo were stably inherited through successive cell divisions in imaginal wing discs.
"Jen is recovering fully and stably".
