The transcriptional profile of pancreatic islets was significantly different from that of other neuroectodermal tissues (i.e., retina, olfactory bulb, cerebral cortex, or hippocampus) isolated from the same RasGrf1 KO mice but, remarkably, shared with all of them a common alteration involving the significant transcriptional repression of the Pttg1 locus.
A major application of GRY53/7HC is to examine how different competitive inhibitor chemotypes, which remarkably share the same active site pocket, seem to be associated with different conformations of the enzyme.
Much of what we consider the American way of life is rooted in the period of remarkably broad, shared economic growth, from around 1900 to about 1978.
Remarkably, many shared that they have simply stopped talking about this issue, not because of a lack of significance or commitment to the issue, but because it has become extremely painful and isolating to talk about something that affects their whole world, professionally and socially, especially when many others believe that they are simply complaining over nothing.
Sheila Dabney, who supplies the voices of three of the contemporary women, is remarkably compelling, sharing heartbreaking stories without self-pity from victims who are often defeated but never destroyed.
Remarkably, they share high similarity with the anti-insect toxin Birtoxin from Parabuthus transvaalicus.
The predicted protein sequences of the four genes are remarkably similar, sharing 84.4% to 89% identity.
While it remains to be investigated why the cellular consequences of depleting these three components differ to some extent, remarkably, they share the net result of increasing surface to volume ratio within the thermal range, thus mimicking the situation in the wild-type beyond the thermal limits.
They shared remarkably consistent symbolic and ideological systems despite a vast territory, including an undeciphered script, standardized weights, measures, sanitation and subsistence systems, and settlement planning.
Phylogenic analysis and multiple alignments have shown that both genes shared remarkably higher degree of structural conservation and sequence identities with other counterparts from invertebrates and vertebrates, further supporting that the two proteins were novel members of molecular chaperone family.
Remarkably the LB shared 37.8% of its proteins with the melanosome but only 9.9% with lamellar bodies from the skin.
