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RESULTS: SPRET/Ei mice, derived from the Mus spretus species, are remarkably more resistant to LPS injection than the commonly used laboratory C57BL/6 mice.
Compared with the WT control mice, the Peli1-KO mice were remarkably more resistant to VSV infection, as revealed by the much improved survival rate (Fig. 4a).
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Remarkably, in Nfatc2 -/- T cells which are more resistant to anergy induction than wild type T cells, the expression of approximately 35 genes – including E3 ligase genes – was reduced implying a specific role for NFATc2 in anergy induction.
Remarkably, SETD8's C270S mutant is around 10-fold more resistant to the inhibition of SPS8I1 and SPS8I2 (Supplementary Figure S2b,c) and shows different Hill coefficients in comparison with native SETD8 (Supplementary Figure S2b d).
Remarkably, in comparison to the HFs the Hdac1Δ/Δep Hdac2Δ/+ep IFE seemed to be more resistant to p53-induced apoptosis.
Interestingly, the two proteins with insertions displayed two additional properties compared to their C-terminal fusion counterpart: (i) they were more resistant to degradation by endogenous proteases and, (ii) even more remarkably, the TEM-1 moiety was stabilized against urea denaturation through the binding to MalE of maltose, that is, its natural ligand.
Others are more resistant.
Conservative Republicans are more resistant.
English firefighters are more resistant to change.
But some museums are becoming more resistant.
New, more resistant species have been identified.
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