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Taken together, our in vivo experiments demonstrate that the application of Cas9 nickase almost avoids DSBs when guided by one sgRNA, and thus can remarkably limit off-target mutations.
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Pitt's experience was remarkably limited.
Most big illusions, similarly, involve a remarkably limited, though resourcefully manipulated, arsenal of mirrors and lights.
And the nuclear diffusion that has transpired has had remarkably limited, perhaps even imperceptible, consequences.
Yet despite all the commentary, the range of viewpoints Americans are offered is remarkably limited.
True, the menu is remarkably limited: $6 pulled-pork sandwiches and a $14 pork plate with braised greens, corn bread and red beans.
But for the most part public interest and understanding of what American soldiers do on our behalf remains remarkably limited in wars that go mostly untelevised and undernoticed.
With "plunging incomes, rising poverty and unemployment, the political consequences of this and the incidence of social unrest in the region have been remarkably limited thus far," notes the EIU.
Have we become blind because we have had an overdose of dark fairytales?" While plenty of foreign tourists go to Bremen to soak up the atmosphere of the Town Musicians of Bremen tale, or to Sababurg's 14th-century Sleeping Beauty Castle, German interest in the tales and the paraphernalia surrounding them is remarkably limited.
But the president's powers, as the book stresses, are remarkably limited, qualified not just by Congress and the courts but also by the states and the localities.The big change coming is not the end of American exceptionalism but the end of American triumphalism.
However, our knowledge about Africa's current role in the global carbon cycle remains remarkably limited.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com